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Fig. 8 | Insights into Imaging

Fig. 8

From: Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation

Fig. 8

a–d Undifferentiated endometrial carcinoma with NE differentiation (FIGO III-C1; involvement of pelvic nodes). A 67-year-old female complaining of metrorrhagia. Axial T2-weighted MR images (a, b). Endometrial tumour prolapsing into the cervical canal, without invasion of the cervical stroma and myometrium. The tumour extends bilaterally through the lumen of the tubes to the parametrial tissues (arrows). A left obturator lymph node is also seen (arrowhead). H&E section of the tumour with a solid pattern composed by large cells with pleomorphic nuclei, mitoses and scarce cytoplasm (c). These cells have small chromogranine-positive granules (d) and small synaptophysin granules in the cytoplasm (not shown) and are strongly positive for pancytokeratin CAM 5.2 (not shown)

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