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Insights into Imaging
Fig. 5 | Insights into Imaging

Fig. 5

From: Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation

Fig. 5

a–e Cervical small cell carcinoma (FIGO II-A; invasion of the upper two-thirds of vagina with no parametrial invasion). A 41-year-old female complaining of vaginal bleeding after intercourse. Sagittal T2-weighted MR image (a), axial T2-weighted MR images (b) and sagittal diffusion weighted image (DWI), b–(c) Retroverted uterus with an anterior cervical tumour, highly restrictive on DWI. No parametrial invasion is noted, but huge, bilateral obturator lymph nodes are found (arrows). The left ovary shows follicular activity and is posteriorly displaced (arrowhead). In this H&E section the cervix is occupied by a solid tumour, composed of small cells, with uniform nuclei and scarce cytoplasm (d). Some tumour cells show positive cytoplasmatic staining for synaptophysin (e) and for chromogranin (not shown)

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