Fig. 1

a–e Struma carcinoid of the right ovary. A 49-year-old female complaining of pelvic and lower abdominal pain. Ultrasound (a) and axial enhanced CT image (b). Large, heterogeneous, mixed tumour of the ovary, predominantly solid, with necrotic areas and calcifications. The solid portions are moderately echogenic on US and hyperdense on enhanced CT, while cystic areas are anechogenic on US and hypodense on CT. No ascites are found. This tumour is composed of areas of thyroid tissue and carcinoid (H&E), the latter having acinar and trabecular architecture (c). The neuroendocrine cells have very uniform nuclei and scarce cytoplasm. The tumour cells show positive cytoplasmatic staining for chromogranine (d) and for synaptophysin (not shown). The thyroid area with compact folicular structure presents intense immunoreactivity for thyroglobulin (e)