Table 1 Pharmacological and pharmacokinetic parameters of iodinated CM [23]

Amidotrizoic acid

 (Urografin),

 1955

146

Yes

Yes

710

2.2 @ 20 °C 1.4 @ 37 °C

30

120

Ioxitalaminic acid

 (Telebrix),

 1969

350

Yes

Yes

2.130

15.1 @ 20 °C 7.5 @ 37 °C

^c

66

Ioxaglate

 (Hexabrix),

 1979

320

Yes

No

600

7.5 @ 20 °C 2.2 @ 37 °C

15

60

Iopromide

 (Ultravist),

 1979

370

No

Yes

770

22.0 @ 20 °C 10.0 @ 37 °C

3 (1–5)

120

Iohexol

 (Omnipaque),

 1983

350

No

Yes

780

23.3 @ 20 °C 10.6 @ 37 °C

^c

120

Iotrolan

 (Isovist),

 1988

300

No

No

320

16.4 @ 20 °C 8.1 @ 37 °C

^c

^c

Ioversol

 (Optiray),

 1989

350

No

Yes

790

14.5 @ 25 °C 8.0 @ 37 °C

^c

96-120

Iomeprol

 (Iomeron),

 1994

350

No

Yes

618

14.5 @ 20 °C 7.5 @ 37 °C

10-35 & 90–130 ^b

110

Iobitridol

 (Xenetix),

 1995

350

No

Yes

915

21.0 @ 20 °C 10.0 @ 37 °C

^c

108

Iodixanol

 (Visipaque),

 1995

320

No

No

290

25.4 @ 20 °C 11.4 @ 37 °C

21

120