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Table 1 A comparison of the four different radiological modalities regarding the ability to depict cystic fibrosis changes of the lungs (yes or no), as well as for cost; need for anaesthesia in young children; detail of information provided by the imaging modality; simplicity of the examination procedure; and radiation dose [6, 46, 47]. The approximate cost for each modality (derived from the price list of Skåne Regional Council, Sweden) was compared with the cost of a frontal and lateral radiograph, which was given the factor 1

From: Radiography, tomosynthesis, CT and MRI in the evaluation of pulmonary cystic fibrosis: an untangling review of the multitude of scoring systems

   Radiography Tomosynthesis CT MRI
Evaluated abnormalities:
 Lung volume Increased lung volume Yes Yes Yes No
Emphysema No No Yes No
Air trapping (expiratory images) No No Yes No
 Bronchial wall thickening   (Yes)a Yes Yes (Yes)b
 Bronchiectasis Mucus plugging/ radiography (Yes)a Yes Yes (Yes)b
 Mucus plugging    Yes Yes Yes
 Parenchyma Consolidation Yes Yes Yes Yes
Atelectasis Yes Yes Yes Yes
Cysts/Bullae (Yes)a Yes Yes (Yes)a
Abscesses (Yes)a Yes Yes Yes
Thickened intra-/inter-lobular septa No No Yes No
Mosaic perfusion No No Yes No
Ground glass opacities No No Yes No
 Pulmonary perfusion   No No No Yes
 Pleural affection   Yes Yes Yes Yes
 Cost, compared with radiography   1 1.1 5.5 10.7
 Anaesthesia required for young children   No Yes (Yes)c Yes
 Detail of information   Low Medium High Medium
 Quick and easy to perform   Yes Yes (Yes)c No
 Mean radiation dose (mSv)   0.09−0.1 0.12−0.13 7−8 0
  1. a Using radiography and MRI these changes are inferiorly discerned, compared with tomosynthesis and CT
  2. b MRI cannot differentiate between bronchial wall thickening and bronchiectasis, especially in the lung periphery [9]
  3. c Depending on the CT system used