Table 2 Details of cases in which 18F-FDG PET-CT had a major impact on clinical management
Stage | Findings on CT | Findings on 18F-FDG PET-CT | Management alteration by PET-CT | |
|---|---|---|---|---|
III | Suspicious cervical lymph nodes and ‘benign’ pulmonary nodule | Cervical nodal metastases and pulmonary metastasis | Surgery | Palliative radiotherapy |
III | Solitary site of disease in the supraclavicular fossa | Extensive locoregional soft tissue and nodal disease | Surgery | Chemotherapy |
III | Bilateral axillary masses | Nodal, intramuscular, hepatic and bone metastases | Surgery | Chemotherapy |
IV | Suspicious pelvic and splenic lesions | Necrotic pelvic lymph node. No focal FDG uptake in the spleen | Chemotherapy | Surgery |
IV | Pelvic abnormality | No focal FDG uptake | Surgery | Routine follow-up |
IV | Solitary splenic metastasis | Nodal, subcutaneous, solid visceral and small bowel metastases | Surgery | Chemotherapy |
IV | Axillary nodal disease and indeterminate pancreatic mass | Axillary nodal disease and pancreatic metastasis | Surgery | Chemotherapy |
IV | Solitary adrenal metastasis and chronic middle lobe atelectasis | Adrenal and middle lobe metastases | Surgery | Chemotherapy |
IV | Solitary hepatic metastasis | 2 hepatic metastases not amenable to surgical resection | Surgery | Chemotherapy |
IV | Solitary hepatic metastasis | 2 unilobar hepatic metastases | Surgery | Extended hepatic surgery |
IV | Iliac pedicle lymph node metastasis | Extensive locoregional nodal disease and femoral bone metastasis | Surgery | Chemotherapy |
IV | Lung and mesenteric nodal metastasis. ‘Hyperdense’ renal cysts | Pulmonary, nodal, gastric, gallbladder, renal and peritoneal metastases | Surgery | Chemotherapy |
IV | Suspicious locoregional nodes. | Extensive locoregional nodal, subcutaneous and intramuscular metastases | Chemotherapy | Chemoradiotherapy |
IV | Subcutaneous, solid visceral and pulmonary metastases | Additional sites of metastatic disease including bone metastases | Trial chemotherapy | Chemotherapy |
IV | Multiple subcutaneous metastases only | Additional sites of subcutaneous disease and bone metastases | Trial chemotherapy | Chemotherapy |
IV | Suspicious iliac chain and retroperitoneal lymph nodes | Extensive locoregional nodal disease | Surgery | Chemotherapy |
IV | Solitary hepatic metastasis | Numerous hepatic and bone metastases | Surgery | Chemotherapy |
IV | Unilobar hepatic metastases | Bilobar hepatic metastases | Surgery | Chemotherapy |
IV | Anterior abdominal wall and breast metastases | Several additional soft tissue metastases | Surgery | Extended surgery |
IV | Unilobar hepatic metastases | Widespread hepatic metastases and sacral bone metastasis | Surgery | Chemotherapy |
IV | Solitary chest wall metastasis | Right axillary subcutaneous and supra-diaphragmatic nodal disease | Surgery | Chemotherapy |