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Insights into Imaging

Table 1 Comparison of radionuclide imaging and MRI as molecular imaging systems [28]

From: Current paradigm of the 18-kDa translocator protein (TSPO) as a molecular target for PET imaging in neuroinflammation and neurodegenerative diseases

Imaging modality

Physiological parameter

Sensitivity

Spatial resolution (mm)

Minimal amount of tracer (or contrast agent) used

PET

Biochemical

pM

1–5

ng

SPECT

Biochemical

pM

1–10

ng

MRI

Proton density

μM

0.1–1a

μg to mg

  1. p pico (10−12), µ micro (10−6), n nano (10−9)
  2. a1-3 mm for fMRI and 5–10 mm for MRS
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