Fig. 4From: Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applicationsa Longitudinal B-mode US scan of the intestinal involved segment with a multilayered appearance. Hyperechoic submucosa (S). b Longitudinal US scan in the contrast-specific mode before contrast agent administration, with the signal almost completely suppressed by the software. Note that the submucosa (S) can be seen. c Diffuse transmural contrast enhancement is seen after specific contrast agent injection. Arrows point to the anterior and posterior thickened intestinal wallBack to article page