Fig. 15From: Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applicationsA 37-year-old man with recurrent CD and obstructive signs. a Longitudinal US scan demonstrates marked thickening of the neoterminal ileum (arrows) with dilated proximal loop. b CEUS at 20 s after injection shows intense enhancement of the inner layers of the wall, with absence of contrast in the muscularis propria (m). It is associated with an increased number of adjacent mesenteric vessels (comb sign) (arrows), a finding described in CT and MRI studies as suggestive of active lesions. c Correlative image of MDCT shows the thickened enhancing wall of the stenotic segment with a stratified appearance (target sign) (arrows). Pathological analysis of the surgical specimen showed coexistence of inflammatory and fibrous componentsBack to article page