Fig. 6

Radiation pneumonitis. a Chest radiograph showed an area of consolidation in the right lung with an air bronchogram. There was also loss of volume of the right lung. b CT showed the therapy response of the tumour. There was patchy distribution of a crazy-paving pattern with increased lung attenuation (ground-glass opacity) and thickening of the interlobular septa in the right lung (1). c Radiological-histopathological correlation. Histological examination after autopsy showed airspace filling with an exudate in combination with thickening of the interlobular septa (arrow), thickening of the interstitium surrounding the airspaces and also the presence of irregular fibrosis (dotted arrow). Alveolar spaces filled with an exudate of proteinaceous material were responsible for the ground-glass opacities on CT. The reticular pattern was due to congestion of capillaries and oedema of the interstitium