Minimally invasive image-guided therapy for inoperable hepatocellular carcinoma: What is the evidence today?

Insights into Imaging

Table 2 Survival data from randomized controlled trials investigating TACE in HCC patients

Study	Patients (n)	Therapy	1-year overall survival (%)	2-year overall survival (%)	3-year overall survival (%)
Lin et al. (1988)[119]	63	21 TAE	42	25	NR
		21 TAE + 5-FU iv	20	20	NR
		21 5-FU iv	13	13	NR
Pelletier et al. (1990)[120]	42	21 TACE	24	NR	NR
Pelletier et al. (1990)[120]	42	21 Conservative	31	NR	NR
Groupe d’Etude (1995)[121]	96	50 TACE	62	38	NR
Groupe d’Etude (1995)[121]	96	46 Conservative	43	26	NR
Pelletier et al. (1998)[122]	73	37 TACE	51	24	NR
Pelletier et al. (1998)[122]	73	36 Tamoxifen	55	26	NR
Lo et al. (2002)[117]	79	40 TACE	57	31	26
Lo et al. (2002)[117]	79	39 Conservative	32	11	3
Llovet et al. (2002)[116]	112	40 TACE	82	63	29
		37 TAE	75	50	29
		35 Conservative	63	27	17

TACE = transcatheter arterial chemoembolization, TAE = transcatheter arterial (bland) embolization, NR = not reported