Table 3 Diagnostic performance in staging various fibrosis and grading various inflammatory activity in training and validation cohorts

Training cohort

 c

φ

 ≥ S1

1.60 m/s

0.96 (0.92–0.99)

85.6

100

≥ G2

0.75 rad

0.72 (0.63–0.81)

60.2

76.9

 ≥ S2

1.73 m/s

0.86 (0.78–0.92)

77.8

75.7

≥ G3

0.79 rad

0.88 (0.83–0.94)

81.1

76.7

 ≥ S3

1.76 m/s

0.89 (0.84–0.95)

91.8

78.1

G4

0.85 rad

0.92 (0.87–0.98)

85.7

85.9

 S4

1.80 m/s

0.88 (0.83–0.93)

92.3

72.8

Validation cohort

 c

φ

 ≥ S1

1.67 m/s

0.76 (0.65–0.93)

100

62.3

≥ G2

0.72 rad

0.76 (0.61–0.90)

75.5

70.0

 ≥ S2

1.67 m/s

0.80 (0.79–0.97)

73.5

85.7

≥ G3

0.81 rad

0.92 (0.85–0.98)

76.0

92.1

 ≥ S3

1.78 m/s

0.83 (0.70–0.92)

64.2

83.3

G4

0.84 rad

0.90 (0.82–0.98)

100

80.7

 S4

1.84 m/s

0.82 (0.72–0.92)

71.4

77.1