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Table 1 The baseline characteristics of patients in training and validation cohort

From: Viscoelastic parameters derived from multifrequency MR elastography for depicting hepatic fibrosis and inflammation in chronic viral hepatitis

Characteristic

Training cohort

Validation cohort

p value

General

170a

63a

 

 Gender

135:35a

47:16a

0.04*

 Age(years)

56 (54–58)

57 (54–60)

0.69

Biochemical data

 BMI(kg/m2)

23.92 (23.56–24.47)

23.64 (22.95–24.34)

0.75

 PLT(×109/L)

149.54 (137.64–161.40)

142.49 (127.82–157.35)

0.19

 ALT(IU/L)

51.29 (38.58–63.95)

72.01 (54.75–89.29)

0.005*

 AST(IU/L)

48.82 (36.92–60.72)

59.19 (26.89–91.49)

0.27

 TB(µmol/L)

20.33 (17.61–23.01)

28.53 (21.88–35.19)

0.009*

 DB(µmol/L)

5.66 (3.65–7.67)

8.26 (4.41–12.09)

0.09

 APRI

1.36 (0.88–1.83)

1.03 (0.86–1.20)

0.68

 FIB-4

3.65 (2.91–4.39)

3.94 (1.48–6.40)

0.59

Histopathology

 Fibrosis stage

  S0

10a

1a

 

  S1

23a

11a

 

  S2

37a

12a

 

  S3

18a

11a

 

  S4

82a

28a

 

 Inflammatory activity

  G0

7a

1a

 

  G1

45a

9a

 

  G2

82a

28a

 

  G3

23a

19a

 

  G4

13a

6a

 
  1. Except where indicated, data are means, with 95% CIs in parentheses
  2. BMI Body mass index, PLT Platelet count, ALT Alanine transaminase, AST Aspartate transaminase, TB Total bilirubin, DB Direct bilirubin, APRI Aspartate transaminase-to-platelet ratio index score, FIB-4 Fibrosis-4 index
  3. *Statistically significant difference between training and validation cohort (p < 0.05)
  4. aData are numbers of patients